Likewise, in diabetes, miRNA-30 is attributed to active participation in the oxidation of fatty acids and endothelial dysfunction, suggesting it as a possible biomarker of coronary microvascular dysfunction [137,140], since the overexpression of miRNA-30 synergizes with exposure to fatty acids, thereby regulating eNOS (endothelial nitric oxide synthase) underexpression, a key regulator of microvascular function at the cardiac level [137]. Here, NOS3 is linked to endothelial dysfunction.