PTEN and neoplasm: The overexpression of miRNA-155 in metastatic breast cancer exosomes suggests its participation in the progression of breast cancer by suppressing the function of tumor suppressors such as PTEN and DUST14 [116,117]; the expression of miRNA-155 found in our study subjects may suggest that patients had a lower progression of breast cancer owing to downregulation, thereby promoting tumor growth and metastasis [118].