Severe patients (n = 6) showed a significant increase in a subset of plasma cytokine/chemokine levels (IL-2, IL-4, IL-6, IL-8, MIP-1β, and TNF-α; ANOVA, p adjusted <0.05 to <0.001) in comparison with the pauci COVID-19 patients (n = 8) and/or controls (Supplementary Figure S2). The gene discussed is TNF; the disease is COVID-19.