DNase-Seq and ATAC-Seq data, which indicate chromatin accessibility to transcription factors; ChIP-Seq data for CTCF; POLR2A; H3K4me3, which indicate active gene transcription; and H3K27ac, which indicates active enhancers, were available in the ENCODE database for the liver and lung tissues, and for the A549 lung adenocarcinoma cell line. The gene discussed is POLR2A; the disease is lung adenocarcinoma.