Positive correlations between the PlGF/sFlt-1 ratio and the quantity of oocytes, embryos, and the OSI were discovered by Nejabati et al. The PlGF/sFlt-1 ratio could be used as a marker to identify high-responder women and could potentially allow for the identification of patients at risk for ovarian hyperstimulation syndrome. The gene discussed is PGF; the disease is ovarian hyperstimulation syndrome.