The team also reported that the intraperitoneal injection of human recombinant IL-37 and the intravenous injection of IL-37 and troponin co-induced dendritic cells can alleviate adverse ventricular remodeling after MI and cardiomyocyte apoptosis in mice, also attenuating the degree of cardiac fibrosis [77]. This evidence concerns the gene IL37 and myocardial infarction.