In the model of LV remodeling after MI, a drug blockade of IL-6, through the administration of the anti-IL6R antibody, decreases neutrophil and macrophage infiltration in the infarct region, and the administration of anti-IL6R antibody after MI suppressed myocardial inflammation resulted in the amelioration of LV remodeling [41]. The gene discussed is IL6R; the disease is myocardial infarction.