First, we found higher levels of lncRNAs: HOTAIRM1, GAS5, MZF1-AS1, and OIP5-AS1 in the allergic asthmatic and obesity-related asthma patients compared with their counterparts’ healthy adolescents and obesity without asthma adolescents, respectively. The gene discussed is MZF1; the disease is obesity due to melanocortin 4 receptor deficiency.