Finally, a rag2 il2rga casper mutant line of zebrafish was suitable for long-term engraftment of human cancer and T cells, allowing it to be used as an anticancer screening platform to quantify responses to a range of cancer immunotherapy approaches, including those involving chimeric antigen receptor (CAR) T cell, bispecific T cell engagers (BiTE), and antigen-peptide epitope conjugate (APEC) approaches [132]. Here, RAG2 is linked to cancer.