We then compared the levels of the ND4/ND1 plasma ratio between the PGC1A-low and the PGC1A-high subjects, and we found that the ND4/ND1 ratio was significantly higher in carcinoma than in hyperplasia patients with high PGC1A levels, but that this was not the case in patients with low PGC1A levels (Figure 7H). This evidence concerns the gene MT-ND4 and carcinoma.