Research has shown that several genes, such as SRY-box transcription factor 9 (Sox9), C-C motif chemokine ligand 20 (Ccl20), C-X-C motif chemokine ligand 1 (Cxcl1), the cluster of differentiation 24 (Cd24) and car-bohydrate sulfotransferase 4 (Chst4) were involved in the aggravation of NAFLD, and their expression increased with disease progression [13]. The gene discussed is CXCL1; the disease is metabolic dysfunction-associated steatotic liver disease.