HIF1A and colitis: In the preventive trial with DSS-colitis, dexamethasone-induced an increase in Hif1a and Il6, and a decrease in Tjp1 expression compared to controls, while Tgfb1 and Vegfa expression was increased in the MTADV group, as well as Nos2 and Tjp1 in comparison to dexamethasone (Figure 5D).