(a)Control group (HF and high-fructose diet (HFFrD) + microcrystalline cellulose 5%(b)HFFrD + GSF (2.5%)(c)HFFrD + HLAB(d)HFFrD+ GSF + HLAB (GSF+HLAB) 10 mL/kg BW, 8 weeks. This evidence concerns the gene HLA-B and hydrops fetalis.