In a preliminary PGRMC1-HA co-immunoprecipitation (co-IP) and mass spectrometric protein identification assay, TSPO was identified as a potential PGRMC1-interacting protein among a list of many identified proteins, so we hypothesized that could be associated with S2R activity in MIA PaCa-2 (MP) pancreatic adenocarcinoma cells. The gene discussed is TSPO; the disease is pancreatic adenocarcinoma.