According to the data of the European Cystic Fibrosis Society Patient Registry (ECFSPR) for 2020, seven pathogenic variants of the CFTR gene are frequent in the European cohort of CF patients, and the relative frequencies of each of which are ≥1% F508del (60.41%), G542X (2.75%), N1303K (2.18), G551D (1.26%), W1282X (1.07%), 2789 + 5G→A (1.07%), and 3849 + 10kbC→T (1.0%) [8]. Here, CFTR is linked to cystic fibrosis.