FBXW7 and rectum neuroendocrine neoplasm: hsa-miR-3934-5p may be strongly implicated in a high mitotic index, which may eventually contribute to higher grade 2 tumors in rectal NETs, whereas hsa-miR-769-5p related to FBXW7 mutation may be involved in grade 1 tumors and is likely to play a role in suppressing rectal NET progression.