Meanwhile, a recent study revealed that the induction of the phosphorylation of IKKα by the ectopic overexpression of MALT1 facilitated the NF-κB subunits’ (p50 and p65) nuclear translocation to promote prostate cancer cell proliferation, invasion, and tumor growth in vitro and in vivo [30]. Here, NFKB1 is linked to Familial prostate cancer.