Since studies have suggested a positive correlation between ARv7 expression and NF-κB activity in human benign prostatic hyperplasia and CRPC [21,37,42], we continued to study whether ARv7 was involved in the upregulation of MALT1-inducing NF-κB activity in androgen-independent prostate cells. This evidence concerns the gene NFKB1 and benign prostatic hyperplasia.