In the same model of CF treated with LPS and N-formylmethionyl-leucyl-phenylalanine (fMLP), administration of LX2931 restored elevated levels of interferon-gamma (IFN-γ), interleukin 12 (IL-12), interleukin 10 (IL-10) and keratinocyte-derived cytokines (KC). This evidence concerns the gene IFNG and cystic fibrosis.