In this study, we demonstrated that DGM could inhibit TGF-β1-induced proliferation of A549 cells, suggesting that DGM could slow down the development of pulmonary fibrosis at some level by inhibiting the proliferation of type II epithelial cells in the presence of injury, thereby reducing the occurrence of the EMT process. The gene discussed is TGFB1; the disease is pulmonary fibrosis.