Leukopenia and the presence of anti-EA (D) IgM were potential as well as independent predictors of remission and LLDAS in SLE patients with active rash at enrollment (excluding patients with alopecia and mucosal ulcerations only) (RR = 26.313, 95% CI RR = 1.65–973.87, p = 0.021, RR = 40.097, 95% CI RR = 1.65–973.87, p = 0.023, respectively). The gene discussed is CD40LG; the disease is Decreased total leukocyte count.