Comparisons of ADAM10 levels between early-onset versus late-onset AD cases (Table 3) produced significantly different results in samples from the first kit: late-onset cases (2.0 ± 0.3 ng/mL, mean ± SD) had lower levels than the early-onset group (2.3 ± 0.2 ng/mL, p = 0.012). The gene discussed is ADAM10; the disease is Alzheimer disease.