Leng et al. [129] used a thiolated version of the CL4 RNA aptamer [126] targeting EGFR to decorate DSPE-PEG2000 nanomicelles loaded with salinomycin, an antibacterial and coccidiostat ionophore drug which showed potent therapeutic activity against cancer stem cells (CSCs) in various tumors [139]. Here, EGFR is linked to cancer.