The results of the chord diagram in human tissue with COVID-19 showed the transcriptional signature of pro-inflammatory markers, such as nfkbiab, tnfa, il1b, and il6, including the genes romo1 (reactive oxygen species), coa1 (cytochrome c oxidase 1), and slc2a1a (glucose transporter 2) involved in the processes of reactive oxygen species production, mitochondrial respiratory chain, and cell membrane glucose transport (Figure 1B). This evidence concerns the gene COA1 and COVID-19.