The ability of different readthrough inducers to restore the expression of full-length COL17 protein in keratinocytes from patients with junctional epidermolysis bullosa was recently assessed by Has et al. The researchers focused their attention on a subset of patients carrying homozygous nonsense mutations in the COL17A1 gene (p.W464*, p.R688*, p.R1226*, p.S140*). Here, COL17A1 is linked to epidermolysis bullosa.