★ Amelioration of aristolochic acid (AA)-induced acute kidney injury through NRF2 pathway [130]★ Coordinated induction of NRF2 target genes, including NQO1, GCLC, GSTpi1/2, and 4 protects against iron nitrilotriacetate (FeNTA)-induced nephrotoxicity [131]. Here, GCLC is linked to acute kidney injury.