★ Prevention of type 2 diabetes-induced nephropathy via AMPK-mediated activation and NRF2 antioxidation [115]★ Attenuation of experimental diabetic nephropathy involves GSK-3β/Fyn/NRF2 signaling pathway [149]Amelioration Diabetes-Induced Renal Fibrosis through Epigenetic Up-Regulation of BMP-7 [150]. This evidence concerns the gene BMP7 and type 2 diabetes mellitus.