Figure 5B shows that treatment with EVO significantly decreased the tumor size compared with PBS treatment in tumor-bearing mice. Furthermore, EVO treatment increased the expression of E-cadherin (Figure 5D), but decreased the expression of N-cadherin (Figure 5E), vimentin (Figure 5F), and Snail (Figure 5G) in the tumor tissues of mice receiving EVO treatment. The gene discussed is SNAI1; the disease is neoplasm.