Dysfunctions in glutamatergic neurotransmission systems and mitochondrial dysfunctions have been implicated in the emergence of these symptoms in SZ [53,54,55]; however, to the best of our knowledge, no studies are available for PHB2 protein in this context and more studies are needed to elucidate by which mechanisms PHB2 could contribute to the cognitive impairments observed in SZ. The gene discussed is PHB2; the disease is Cognitive impairment.