In the present study, most of the hypercreatinemic patients with COVID-19 were found to have hyper-inflammatory status and coagulopathies, as these patients were having elevated levels of LDH, ferritin, D-Dimer, procalcitonin, Hs-CRP, and IL-1 and IL-6 compared to hypercreatinemic patients with COVID-19. The gene discussed is CRP; the disease is blood coagulation disease.