Furthermore, we did so in subsets of the material defined by the presence and distribution of CD45+ cells, i.e., ‘inflamed’ (CD45+ cells throughout the tissue), ‘immune-excluded’ (CD45+ cells throughout the surrounding stroma but not in cancer cell islets), and ‘desert’ (no/very few CD45+ cells) phenotypes of NPC. The gene discussed is PTPRC; the disease is cancer.