First, in B-ALL case #03 with complex karyotype and BCR::ABL1 fusion, OGM detected infrachromosomal deletions characteristic of B-ALL, namely recurrent deletions in IKZF1, PAX5, BTG1, ADD3 genes, and CDKN2A biallelic deletion (Figure 4) [21]. This evidence concerns the gene ADD3 and acute lymphoblastic leukemia.