AKT1 and neoplasm: The anti-malignancy impacts of Baicalein are thought to be because of the transfiguration of many signaling axes, as well as the PI3K/AKT, which inhibits cellular growth while eliciting apoptosis, stimulation of the caspase cascade, and the intrinsic (mitochondrial) apoptotic trail [67,68], and DNA breakdown in tumor tissues [69,70].