The breast cancer incidence between 25–40 years was previously observed at around 26% for BRCA1 and 17% for BRCA2 GPV carriers in our population by Van der Kolk et al., whereas between 40 and 55 years, a breast cancer incidence of 30% was observed in BRCA1 and 42% for BRCA2 GPV carriers [22]. This evidence concerns the gene BRCA2 and breast cancer.