On the other hand, STK38L expression is elevated in a subset of primary PDACs (Pancreatic ductal adenocarcinomas) and PDAC cell lines displaying the aberrantly differentiated endocrine exocrine (ADEX) subtype characteristics including overexpression of mutant KRAS, and depletion of STK38L in a subset of ADEX subtype cell lines inhibits cell proliferation and induces apoptosis [69]. Here, STK38L is linked to pancreatic ductal adenocarcinoma.