ALB and neoplasm: Because of its highly metastatic nature, it is assumed that the main mechanisms of metastasis of splenic HSA are via the hematogenous route or by seeding cells in organs of the abdominal cavity due to tumor rupture [1,5,15,86,87,93], with the liver, omentum, peritoneum, lung, right atrium, and brain being the most common sites of metastasis [108], and less commonly in bones and skeletal muscle, as reported by Carloni et al. (2019) [44].