YAP1 and cancer: Incubating PC-3 cancer cells in direct contact with fibroblast cell lines induces changes in gene expression patterns in several pathways, including Rho, the Yes-associated protein (YAP)/transcriptional coactivator with PDZ-binding motif (TAZ) cascade, pro-inflammatory signaling through NFκB, and TGFβ signaling, and the transcription factor RELA.