In BC, exosomes induce resistance to angiogenesis inhibitors through the transfer of VEGF [262], the proliferation of CAFs through the transfer of miR105 from BC cells [263], the transfer of miR200c/114 and miR126a from cancer-to-cancer cells [258], from cancer to endothelial cells, TH1 T cells [259] and NK cells [257], resulting in local suppression of the immune response [246]. Here, VEGFA is linked to breast cancer.