KDR and Miyoshi myopathy: For instance, VEGF released by MM cells binds to VEGF receptor 2 (VEGFR2) on endothelial cells (ECs) of MM patients (MMECs) and to VEGFR1 on BMSCs, triggering their proliferation, chemotaxis as well as the release of other angiogenic cytokines sustaining the VEGF-paracrine loop [16].