CDK1 and acute myeloid leukemia: Our data showed that the following pathways from the library under study regulated BM stromal-mediated mechanisms of AML resistance to daurorubicin: PKC kinase, PI3K/Akt, JAK I, CDK1/2/4, and Src kinases, as well as the activity of the nuclear export receptor CRM1/XPO1 (Table 1 and Figure S5).