We then calculated the average correlation (mean R value) across the five tumour types (Supplementary Table S6) and identified eight TARGET genes (MSH2, ATR, MSH6, BRCA1, EZH2, BRCA2, AURKA, and NPM1) whose expression positively correlated with XPO1 expression in all the tumour types analyzed (Figure 7) that were considered as potential targets in co-treatments with KPT-330. Here, MSH6 is linked to neoplasm.