The CAR-M structure was a CD3ζ-based CAR with a scFV to target HER2, and they found that the HER2-CAR-M cells exhibited antigen-specific phagocytosis of HER2+ beads and SKOV3, a HER2+ ovarian cancer cell line, in a dose- and time-dependent manner [404], and that cells from 20 representative normal tissues were not phagocytosed. The gene discussed is ERBB2; the disease is ovarian carcinoma.