Multivariate analysis revealed that creatinine (HR: 1.267, p = 0.003), AFP >200 ng/mL (HR: 1.745, p < 0.001), vascular invasion (HR: 1.621, p < 0.001), tumor size > 5 cm (HR: 1.863, p < 0.001) and ALBI grades 2–3 (HR: 1.541, p < 0.001) were linked with decreased OS. The gene discussed is AFP; the disease is neoplasm.