Moreover, up-regulation of proapoptotic proteins (B-cell lymphoma-2 protein-BCL-2, C-X-C motif chemokine ligand 10- CXCL10, and C-C motif chemokine ligand 2- CCL2) as well as interleukin 6 (IL-6) were presented as molecular alterations associated with lymphopenia in patients with this infection [51]. The gene discussed is CCL2; the disease is infection.