We aimed to investigate the influence of preclinical complications such as ascites and encephalopathy and KIR genetic characteristics on death due to sepsis, multiorgan failure (MF), and graft failure (GF) in patients with CA undergoing LTs to develop preventive actions and improve and/or modify treatments to increase the survival of the transplanted patient. This evidence concerns the gene KIR3DL1 and Encephalopathy.