This cluster was characterized by a less severe MIS-C phenotype with a lower prevalence of hypotension/shock, lower CRP, ferritin, NT-proBNP, and D-dimer levels, less hyponatremia and thrombocytopenia, no ventricular dysfunction, and few chest X-ray abnormalities compared to the other clusters. This evidence concerns the gene NPPB and Hyponatremia.