Several risk factors for PICU admission have been identified, including age (≥ 6 years), ethnicity (Black patients), respiratory symptoms, gastrointestinal involvement, and certain laboratory features, including high C-reactive protein (CRP), troponin, ferritin, D-dimer, N-terminal B-type natriuretic peptide (NT-proBNP), interleukin (IL)-6 levels, thrombocytopenia, and lymphopenia [10]. This evidence concerns the gene CRP and Thrombocytopenia.