Most of the DEGs were overexpressed in PCOS compared to the control group, including METTL14, WTAP, VIRMA, ZC3H13, RBM15, CBLL1, YTHDC1, YTHDC2, YTHDF1, YTHDF3, HNRNPC, FMR1, IGFBP1, ELAVL1, and FTO, and several other DEGs such as METTL3, RBM15B, HNRNPA2B1, IGFBP2, IGFBP3, IGF2BP1, and ALKBH5 were downregulated in PCOS. The gene discussed is METTL3; the disease is polycystic ovary syndrome.