Although novel insights into the interaction of VDR and the Wnt/β-catenin pathway exerting antitumour effects have been obtained [29, 30], the molecular mechanisms underlying VDR regulating invasion and apoptosis through the Wnt/β-catenin signalling pathway in CRC remain unclear and must be further elucidated. The gene discussed is VDR; the disease is colorectal carcinoma.