We found, however, that IL-6 (Fig. S3A–G) and IL-6 signaling (Fig. S3H–M) were dispensable for inhibiting lung Th2 cell accumulation and allergic eosinophilic inflammation in response to HDM contaminated with 400-fold higher levels of LPS (i.e., 0.4 mg LPS per 1 mg HDM; HDMLPS400). This evidence concerns the gene IL6 and inflammation.