Using PSD-95 (postsynaptic density protein 95) and CaMKIIα (calcium/calmodulin-dependent protein kinase II alpha subunit) (Table S2), two dendritic G4-mRNAs that bind TDP-43 in vivo26,27, we determined the effects of 10 ALS-linked amino acid substitution mutations20. The gene discussed is DLG4; the disease is amyotrophic lateral sclerosis.