NF-kB level was significantly higher in ITP patients who did not respond to steroids compared to responders (P = 0.005), and It was significantly higher in patients who needed transfusion compared to those who did not (202.74 ± 37.14 vs.177.46 ± 36.93; P = 0.045) (Table 2). The gene discussed is NFKB1; the disease is autoimmune thrombocytopenic purpura.