By sequencing the transcriptome of pulmonary tissue in the model and to confirm the role of the IL-17 pathway in PF mice and the influence of the related genes of QLT, the mRNA level of IL-17, CCL12, FOSL1, MMP9, CXCL5, and AREG in pulmonary tissue was determined. Here, MMP9 is linked to pemphigus foliaceus.