The pSTR in the intron of UBE2L3, a member of the E2 ubiquitin-conjugating enzyme family, was mostly expanded in individuals from East Asia (Fig. S27a), and this pSTR was in strong LD with several GWAS SNPs implicated in multiple phenotypes, such as Crohn’s disease, high-density lipoprotein cholesterol levels, and systemic lupus erythematosus (Supplementary Data 6). The gene discussed is UBE2S; the disease is Crohn disease.