CD101 and neoplasm: In contrast, in the irradiated tumor, effector-like CD101-TCF1-TIM3+PD1+ cells, which in chronic viral infection have been shown to constitute a transitory population between stem-like and terminally exhausted cells3, increased most (threefold) compared to RT/anti-PD1, whereas stem-like cells did not further increase compared to RT/anti-PD1 (Fig. 3h, i).