It is suggested that Etv1 is involved in different processes in multiple malignant tissues, such as carcinogenesis of prostate cancer, cell survival of gastrointestinal stromal tumor, and metastasis of pancreatic cancer (Tomlins et al., 2005; Chi et al., 2010; Heeg et al., 2016). Here, ETV1 is linked to familial pancreatic carcinoma.