The most potent Mabs in HNSCC are EGFR antagonists and checkpoint inhibitors, especially PD‐L1 antagonists.49, 50, 53, 55, 56, 57, 58, 60, 116, 117, 128, 130, 131, 142, 143, 148, 165, 171, 172, 173. This evidence concerns the gene CD274 and head and neck squamous cell carcinoma.